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The Personalized Medicine Revolution: How Diagnosing and Treating Disease Are About to Change Forever (Englisch) Taschenbuch – 10. Februar 2015

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“Pieter Cullis is one of those rare individuals who can conduct cutting-edge science, see how it fits in the big picture, and explain it all with clear, graceful storytelling. This book is essential reading for anyone—from the novice to the insider—who is seeking to understand how medicine is changing.”—Luke Timmerman, biotechnology journalist and author of the forthcoming book Hood: A Revolutionary Life in Science and Technology

"Cullis will enlighten you as to why personalized medicine will be the greatest technological advance you have ever experienced.” - Rob Wright, Chief Editor, Life Science Leader

“This is a must-read for anyone who wants a glimpse into medicine’s potentially revolutionary future.”—Tom Blackwell, The National Post

Über den Autor und weitere Mitwirkende

Pieter Cullis, PhD, is director of the Life Sciences Institute at the University of British Columbia, chairman of the B.C. Personalized Medicine Initiative, and a professor in the Department of Biochemistry and Molecular Biology at UBC. He has a PhD in physics from UBC and did a post-doc at Oxford University in biochemistry. He is also a recipient of the Prix Galien, Canada’s top award for developing new drugs to treat disease. Iva Cheung holds an MSc from the University of British Columbia and works as a freelance editor. Both live in Vancouver.

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6 von 6 Kunden fanden die folgende Rezension hilfreich
Insights into the new science of genetics and our health and medical care 24. April 2015
Von Martin Dawes (Head, Family Practice, UBC) - Veröffentlicht auf
Format: Taschenbuch
Maybe we can escape our genes but you cannot escape the revolution happening in medicine as it relates to the use of genetic technologies. Every week there is an announcement on the radio or television about some new genetic test as part of personalised medicine . The problem is how to make head or tail of all these announcements and what to expect to see clinically in your hospital or clinic. To help make sense of the deluge of information this book by Pieter Cullis gives the reader an original view of genetics that is written for any reader. Started as a response to the question: “what is this personalised medicine thing?” the book is not a textbook but is stories about people and their discoveries as the science of genetics has made its way into clinical practice. The use of these anecdotes to describe the important discoveries in medicine over the centuries helps the reader understand more about how the science of medicine has advanced and puts into perspective the innovations of personalised medicine. I am relatively new in this field and this book was a genuine pleasure to read as it gave me a new perspective on this exciting field of discovery and practice.
1 von 1 Kunden fanden die folgende Rezension hilfreich
The Future of Personalized Health 18. August 2015
Von James R Kean - Veröffentlicht auf
Format: Kindle Edition
I recently finished reading this book and found it was an excellent summary overview of where we are and where we are currently headed with not only personalized or precision healthcare but also the aspect related to prevention and wellness strategies. The most interesting aspect of where we are is the dropping of costs related to complex testing. This would include all of the various 'omics disciplines (genomics, proteomics, metabolomics, transcriptomics, epigenomics, the environome, the micro biome, etc...). Once the means of data production at the individual level are made more cost effective the amount of data per person will be staggering. The next task will be then to make sense of it all. In the end, the presence of this amount of data will allow professionals to decode actionable results. This approach will transform how practitioners approach individual health management. It will also require a wholesale change in the management of individual data. The current generations of EHRs are inadequate and will need a complete revamping.
1 von 1 Kunden fanden die folgende Rezension hilfreich
This is a beautifully written book with clarity and humor that is easily ... 15. Juni 2015
Von Sandra Schmid - Veröffentlicht auf
Format: Taschenbuch Verifizierter Kauf
This is a beautifully written book with clarity and humor that is easily accessible to the general public poised to benefit from the Personalized Medicine Revolution. Dr. Cullis clearly articulates a realistic vision for both the near and distant future that will change the practice of medicine. We, the public, will be active participants. I purchased 5 copies for bioinformaticians, medical students and family members, who will benefit from reading this book.
An entertaining and exciting read about what lies ahead for patients and healthcare- the future is now! 23. Juli 2015
Von Bryn Hyndman - Veröffentlicht auf
Format: Taschenbuch
In Pieter Cullis’s entertaining and smart new book, The Personalized Medicine Revolution, he lays out the transformation in health care and medicine that is at our doorstep. The new era of personalized, preventative medicine has arrived, and it is astonishing how medicine as we know it – for doctors and patients alike – is being vastly changed.

He defines personalized medicine as being based on the unique molecular makeup of your individual self and a molecular-level understanding of the disorder you may have. It’s your molecular profile, or digital health score, if you will. Simply put, our genetics – our DNA – are being examined in different ways, in different parts of our bodies, to discern what diseases we may be highly susceptible to, and what medications may wreak havoc on us with debilitating side effects.

There is a huge wealth of information in your blood which hasn't been utilized yet.
A well-known example is the choice that actress Angelina Jolie made to have a prophylactic double mastectomy. Genetic analysis of her DNA revealed she was a carrier of the BRCA-1 mutation, and her specific risk of developing breast cancer was 87%. This is an example of a genetic biomarker predicting the likelihood of disease possibility, in this instance cancer. She now has a risk of less than 5%. Not non-existent, but an astronomical improvement.
Biomarkers based on genetic data only provide information on your risk of disease – not whether you have it. But biomarkers from proteins in your saliva, blood and urine can tell you what disease you actually have. There is a huge wealth of information in your blood which hasn’t be utilized yet – but that is changing. The ultimate goal of this medical revolution is to predict and identify disease before it becomes acutely life threatening, and knowing which medicines will work for your unique genetic makeup.
I am excited to see how our health care system and patient experience transforms over the next 5 years!

Bryn Hyndman MD
The future of health care in one easy read 14. August 2015
Von Mark Tracy - Veröffentlicht auf
Format: Taschenbuch Verifizierter Kauf
Cullis has given us a fascinating look into the future of healthcare for all of us. The book presents a multi-faceted, technical subject in clear, simple language, with a dose of humor. It is a must read health care experts and lay people alike.
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