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RNA: Life's Indispensable Molecule
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› Besuchen Sie die Seite von James E. Darnell auf Amazon
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Produktbeschreibungen
Pressestimmen
"At first blush, we would think anyone in the current...RNA science pantheon could write a book like this, but once one takes a look and sees the richness of erudition, the poignancy of detail, the measured nuances, and most of all his elegant writing, combined with the underlying perspective of history, I cannot think of anyone in our RNA community who could have done it more attractively. ...No one could have written the eukaryotic RNA story as well as Jim Darnell. ...This book...will not be supplanted by as glorious a book on RNA anytime soon."
RNA
"Darnell's book on RNA is a masterpiece of scholarship. It deserves an exalted place on the bookshelf of every molecular biologist and biochemist next to other classics like Watson's Molecular Biology of the Gene, Kornberg's DNA Replication, and Judson's The Eighth Day of Creation."
Joe Goldstein, UT Southwestern
"Jim Darnell's career in science covers the 60 or so years following the publication of the Watson-Crick structure of DNA. This remarkable book tells a story that parallels his career, dealing at the beginning with the prehistory of research on RNA, DNA, and proteins and then shifting into high gear with a detailed look at the history of bacterial messenger RNA and the author's own specialty, the RNA of eukaryotic cells....Darnell is an experienced teacher and author of textbooks. His explanations of complex experiments are superb..."
The FASEB Journal
"Darnell has been at the forefront of molecular biology throughout his illustrious career. He leaves no stone unturned in this comprehensive but clear text...The real value of this work, aside from its extraordinarily readable style, is that it covers the history of RNA biology from the early pioneers to the present....The text is supported by high-quality, highly informative figures....up-and-coming students and seasoned researchers alike will gain significant insight into this central field."
Choice
"Darnell's book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences....RNA: Life's Indispensable Molecule should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all."
Joan A. Steitz in Science
Kurzbeschreibung
In RNA: Life's Indispensable Molecule, Jim Darnell provides a comprehensive and captivating account of RNA research, illuminated by his own life-long and celebrated engagement in the field. Darnell describes how scientists unraveled fundamental questions about the biochemical and genetic importance of RNA--how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, and how RNA molecules likely initiated life on Earth. With a scope extending from the early 20th century to the present day, and with the clarity expected from an accomplished textbook author, he conveys the intellectual context in which these questions first arose and explains how the key experiments were structured and answers obtained. The book is geared towards scientists from the graduate level on up, and will particularly appeal to active investigators in RNA biology, educators of molecular biology and biochemistry, and science historians.
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Buchdeckel | Copyright | Inhaltsverzeichnis | Auszug | Stichwortverzeichnis | Rückseite
Buchdeckel | Copyright | Inhaltsverzeichnis | Auszug | Stichwortverzeichnis | Rückseite
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3 von 4 Kunden fanden die folgende Rezension hilfreich
It is mostly about reasearch milstones in the field of RNA research
5. September 2011
Format:Gebundene Ausgabe|Von Amazon bestätigter Kauf
As nowadays we are benefiting from the the many outcomes of high-throughput molecular biology, the articulate hypothesis-driven research is often being neglected. This book provides some interesting glimpse into those historical discoveries regarding the RNA world from an era which was poor in prior knowledge and had to heavily rely on hypothesis-driven research. If you are a student and you look for "fundamentals of the RNA world" of today- you may want to look for other books. Teachers and senior researches will find this book extremely interesting, if they have the time for it.
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