If you've been enjoying the rash of viral/epidemiological titles such as "Hot Zone", "The Coming Plague" or "Deadly Feasts", you'll find a real gem in "Plagues and Peoples". William McNeill, an author with impeccable credentials, is IMHO, the Marshall McCluhan of epidemiological biology. Like McCluhan, he published this work decades before the subject matter became mainstream. He also comes at the topics he investigates with a fresh and brain-stretching approach.
McNeill presents a history of mankind where every civilization is surrounded by a disease 'gradient'. These gradients interact with one another as one of the significant factors in inter-cultural dominance and expansion. The conquest of the New World takes on a new look as McNeill describes the impact of the European disease gradient on a defenseless North America. He contrasts this with the impact of the African disease gradient on Europeans.
Some of McNeills ideas, such as his analogies between micro-parasites (diseases, bugs, etc.) and macro-parasites (governments, barbarians, raiders, etc.) are still fresh and fascinating. Consider his idea that we accept a government as a low-level parasite so that we minimize the impact of rogue parasites like raiders and such in the same way we allow our bodies to be colonized by benign parasites like E.Coli so that we have fewer niches available to rouge germs like staph and strep. This book is filled with exciting ideas like this.
All in all, the book is very readable, adds greatly to any view of history and creates an excellent foundation for the recent titles in this area.