While i can agree that Miller's Anesthesia is some dense reading, this is the anesthesia bible, and there is a reason that it can be your "one anesthesia book." Full of great material that delves deeply into every subject, from the history of opiods to current practice in peripheral blocks, this text will help you to become a knowledgeable provider, in the least. The older edition had a three page discussion on Ketamine, its history, and its full biochemical workings on the body as it is currently understood. This is a rare feature among anesthesia texts, because most feel comfortable simply detailing a drugs effects, contraindications and side effects without explaining fully what it does pharmacodynamically as well as kinetically. It is cumbersome to bring to classes, it's true, but as cover-to-cover reading goes, this is a book that will follow me through the rest of my career.
That being said: if you are a resident, not planning on working in anesthesia, this is *not* the book for you. It is "a lot" as one reviewer put it. A simpler text will get you through your rotation just as well, and take up far less of your valuable study (and sleep) time.
Also, if you are a beginning nurse anesthesia student, this might also not be a good primer in the study, as it is written with a lot of biochemistry and delves deeply into the workings of nearly every system in every chapter. However, that doesn't mean that you shouldn't take a gander at it and decide if it's for you. I feel i can sell my Morgan and Mikhail, my Nagelhout and my Stoelting's after having received this text. It has the answer to nearly every question i've had for it.