Case Studies in Immunology recapitulates major topics of immunology as the background to a selection of real clinical cases that serve to reinforce and extend the basic science. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. The authors have added five new cases to the existing thirty in the previous edition. The cases describe real events from case histories, largely drawn from the records of the Boston Children's Hospital and the Brigham and Women's Hospital. The cases are intended to help medical students and pre-medical students to learn and understand the importance of basic immunological mechanisms. The cases are presented in the same format. The case history is preceded by basic scientific facts that are needed to understand the case history. The case history is followed by a brief summary of the disease under study. Finally there are several questions and discussion points that highlight the lessons learned from the case.
As well as being a valuable revision aid, Case Studies in Immunology introduces in a clinical setting the major common disorders of immunity, including hypersensitivity types I-IV and autoimmune disorders such as lupus and autoimmune diabetes. It also describes and explains the consequences of some of the most important immune deficiencies. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the disease or disorder. An end-of-case summary, questions, and discussion points end each case. Seven new cases have been added to this latest edition: 1. AID (Activation Induced Deaminase) Deficiency 2. NEMO/ I kappa kinase deficiency 3. Terminal Complex Deficiency 4. Autoimmune Polyendocrinopathy- Candidosis- Ectodermal Dysplasia (APECED) 5. Hepatitis C 6. Rheumatoid Arthritis 7. Rheumatic Fever
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