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Biochemistry (Englisch) Taschenbuch – 23. März 2012

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Part I: MOLECULAR COMPONENTS OF CELLS. 1. Chemistry is the Logic of Biological Phenomena. 2. Water-The Medium of Life. 3. Thermodynamics of Biological Systems. 4. Amino Acids. 5. Proteins: Their Primary Structure and Biological Functions. 6. Proteins: Secondary, Tertiary, and Quaternary Structure. 7. Carbohydrates and Glyco-Conjugates of the Cell Surface. 8. Lipids. 9. Membranes and Membrane Transport. 10. Nucleotides and Nucleic Acids. 11. Structure of Nucleic Acids. 12. Recombinant DNA: Cloning and Creation of Chimeric Genes. Part II: PROTEIN DYNAMICS. 13. Enzyme Kinetics. 14. Mechanisms of Enzyme Action. 15. Enzyme Regulation. 16. Molecular Motors. Part III: METABOLISM AND ITS REGULATION. 17. Nutrition and the Organization of Metabolism. 18. Glycolysis. 19. The Tricarboxylic Acid Cycle. 20. Electron Transport and Oxidative Phosphorylation. 21. Photosynthesis. 22. Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway. 23. Fatty Acid Catabolism. 24. Lipid Biosynthesis. 25. Nitrogen Acquisition and Amino Acid Metabolism. 26. The Synthesis and Degradation of Nucleotides. 27. Metabolic Integration and Organ Specialization. Part IV: INFORMATION TRANSFER. 28. DNA Metabolism. 29. Transcription and the Regulation of Gene Expression. 30. Protein Synthesis. 31. Post-Translational Processing of Proteins and Protein Degradation. 32. The Reception and Transmission of Extracellular Information.

Über den Autor und weitere Mitwirkende

Reginald H. Garrett was educated in the Baltimore city public schools and at the Johns Hopkins University, where he received his Ph.D. in biology in 1968. Since that time, he has conducted research and taught biochemistry courses at the University of Virginia, where he is currently Professor of Biology. He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. His early research focused on the pathway of nitrate assimilation in filamentous fungi. His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. More recently, he has collaborated in systems approaches to the metabolic basis of nutrition-related diseases. His research has been supported by grants from the National Institutes of Health, the National Science Foundation, and private industry. A member of the American Society for Biochemistry and Molecular Biology, Garrett is a former Fulbright Scholar, was twice Visiting Scholar at the University of Cambridge, and was Invited Professor at the University of Toulouse, France. Charles M. Grisham received his B.S. in chemistry from the Illinois Institute of Technology in 1969 and his Ph.D. in chemistry from the University of Minnesota in 1973. Following a postdoctoral appointment at the Institute for Cancer Research in Philadelphia, he became Professor of Chemistry at the University of Virginia, where he teaches biochemistry, introductory chemistry, and physical chemistry. He has authored numerous papers and review articles on active transport of sodium, potassium, and calcium in mammalian systems, on protein kinase C, and on the applications of NMR and EPR spectroscopy to the study of biological systems. His work has been supported by the National Institutes of Health, the National Science Foundation, the Muscular Dystrophy Association of America, the Research Corporation, the American Heart Association and the American Chemical Society. A member of the American Society for Biochemistry and Molecular Biology, Grisham held the Knapp Chair in Chemistry in 1999 at the University of San Diego; was Visiting Scientist at the Aarhus University Institute of Physiology, Aarhus, Denmark, for two years; and received a Research Career Development Award from the National Institutes of Health.

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Die hilfreichsten Kundenrezensionen auf (beta) HASH(0x97d0412c) von 5 Sternen 52 Rezensionen
18 von 18 Kunden fanden die folgende Rezension hilfreich
HASH(0x97ef5f30) von 5 Sternen Superb, balanced book. 6. November 2011
Von blargle - Veröffentlicht auf
Format: Gebundene Ausgabe
I took 2 courses in undergraduate biochemistry, and this was the book used. The authors strike a balance between biology (i.e. discussion of regulation and physiology) and chemistry (i.e. reaction mechanisms and structures of proteins). This book is middle-of the line between Voet (hardcore chemistry/structural biology) and Lehninger (physiology/pre-med focus). The illustrations were clear and overall the text was comprehensible. For teaching an undergraduate course in biochemistry, Garrett & Grisham is hard to beat.
28 von 31 Kunden fanden die folgende Rezension hilfreich
HASH(0xa24b9eb8) von 5 Sternen All in all, most suitable for a general audience 14. Dezember 2000
Von hjm - Veröffentlicht auf
Format: Gebundene Ausgabe
Undergraduate biochem at my school is taught by the biochem department (not surprising). However, as a result, we have all sorts of people taking the course from prospective chemists (me) to premeds and general bio sci majors. So the dept. uses this book and it's probably the best compromise out there. Voet and Voet would be perfect if the course was taught exclusively for chemists, Stryer if the course was loaded up with premeds (horrifying thought, I know :) ) But Garrett and Grisham have managed to write a rather well balanced text (one is in UVA's bio dept., the other UVA's chem dept) with plenty of both chemical insight and medical relevance. Based on (I'm sure) similar experiences they've had teaching biochem to a mixed audience, and knowing that most undergrad biochem courses tend to be taught to similar groups of students nationwide, this is the best book for a case like that. (However, I'm getting Voet and Voet as a reference for me personally one of these days.)
21 von 23 Kunden fanden die folgende Rezension hilfreich
HASH(0x97e21bd0) von 5 Sternen Well-written, not-so-hot layout 17. November 2005
Von Daisy Turner - Veröffentlicht auf
Format: Gebundene Ausgabe
My university uses this book for the two-semester biochem sequence for BSc Chemistry/Biochemistry students. It's a well-written book, overall -- lots of information but not a very dense "scientific" read. The best part is the way the authors keep tying things back to reality ... sidebars explain how the dynamics of protein folding affect Alzheimer's disease, or what protease inhibition means for the development of HIV drugs.

The figures are aesthetically pleasing and really help to clarify descriptions in the text. The only problem is that the figures are usually a couple pages away from the text they refer to. For example, when describing the mechanism of chymotrypsin cleavage, it would make a lot more sense to put all the text on the left page and the mechanism/structures on the right page. Instead, the text is about three pages before the mechanism, meaning the reader has to keep flipping back and forth trying to understand what is going on. It's like that in most if not all cases. Not a big deal, but it's the sort of thing the layout editor should have realized when putting the book together. Maybe they'll fix it in the fourth edition.

Regardless, this is a very good biochem book. I'd recommend it for an undergraduate student of chemistry or biochemistry.
8 von 8 Kunden fanden die folgende Rezension hilfreich
HASH(0x97cb7354) von 5 Sternen A scammed feeling 7. September 2013
Von Honestly0114 - Veröffentlicht auf
Format: Gebundene Ausgabe
There are many undesirable issues with this textbook.

First major issue is the fact that it doesn't have example problems that teach the student how to solve problems at the end of the chapters. However, for the price of $45-$100 the student can buy the "solutions manual" which should have already been part of the text. So when purchasing this book, the customer is buying an incomplete textbook.

Second, the examples problems that are present will neglect to explain or show crucial steps in the equations.
Again, more incentive to spend more money on the solutions manual.

Third, issue is that there are typos throughout the book, coincidentally in the example problems and answers to the example problems. There is more confusion and thus incentive to buy the solutions manual. It's very confusing when quantities are mislabled in mili-moles when it should be micro-moles.

Fourth, ball and stick models don't show double and triple bonds in the molecule.

I'm sure they will just make this textbook obsolete with a new edition to correct the typos. Profitable industry where products are not recalled for major mistakes.

In the future, I hope none of my professors will use Cengage textbooks.
9 von 9 Kunden fanden die folgende Rezension hilfreich
HASH(0x97df5534) von 5 Sternen Does not come with OWL! 26. Februar 2013
Von B. Adams - Veröffentlicht auf
Format: Gebundene Ausgabe Verifizierter Kauf
The description and price for this book leads you to believe that it comes with OWL - it does not! Must pay for access code separately.
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