Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.
The emergence and spread of antibiotic resistance is a growing medical and public health emergency. Misuse and overuse of antibiotics is putting us at risk of losing our ability to cure infectious diseases. Karl Drlica and David S. Perlin give an authoritative and thorough explanation of all aspects of antibiotic resistance, from the basic science to the strategies that could minimize resistance problems and extend the life spans of existing antibiotic agents. Intended as the definitive book on a major biomedical issue, Antibiotic Resistance will be required reading for investigators and serious students in microbiology, infectious disease, pharmaceutics, and public health; physicians; and students in pharmacy, medicine, and veterinary medicine.