The Alchemist premiered 34 years after the first permanent public theatre (The Theatre) opened in London; it is, then, a product of the early maturity of commercial drama in London. Only one of the University wits who had transformed drama in the Elizabethan period remained alive (this was Thomas Lodge); in the other direction, the last great playwright to flourish before the Interregnum, James Shirley, was already a teenager. The theatres had survived the challenge mounted by the city and religious authorities; plays were a regular feature of life at court and for a great number of Londoners.
The venue for which Jonson apparently wrote his play reflects this newly solid acceptance of theatre as a fact of city life. In 1597, the Lord Chamberlain's Men had been denied permission to use the theatre in Blackfriars as a winter playhouse because of objections from the neighborhood's influential residents. Some time between 1608 and 1610, the company, now the King's Men, reassumed control of the playhouse, this time without objections. Their delayed premiere on this stage within the city walls, along with royal patronage, marks the ascendance of this company in the London play-world (Gurr, 171). The Alchemist was among the first plays chosen for performance at the theatre. (Quote from wikipedia