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Aglow in the Dark. The Revolutionary Science of Biofluorescence
 
 
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Aglow in the Dark. The Revolutionary Science of Biofluorescence [Englisch] [Gebundene Ausgabe]

Vincent Pieribone , David S. Gruber


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Vincent Pieribone
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Self-illuminating creatures have drawn curiosity since time immemorial, but only a few researchers have conducted experiments to discover the source of their glow. One Raphael Dubois determined in 1887 that it's a chemical reaction, the exact components of which eluded the best efforts of Princeton professor Edmund Newton Harvey. Enter the hero of the authors' story: Osamu Shimomura. A teenage survivor of the nuclear bombing of Nagasaki, he emerged from the ruins as a young biologist in the mid-1950s who had no strong idea of what to study. Handed bluish extract of sea flies by his boss, who added lapidary guidance--"We know nothing about this, just that it glows"--Shimomura solved the problem in a few years. Shimomura's eureka moment is well drawn by the authors, as is their explanation of the chemistry of the green fluorescent protein (GFP) Shimomura isolated. GFP has become a lucrative favorite of biotechnologists, who transformed the study of neural tissue by inventing GFP markers. Writing with warmth and optimism, Pieribone and Gruber will fascinate budding biochemistry students. Gilbert Taylor
Copyright © American Library Association. All rights reserved

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"[A] beautifully illustrated book...The main narrative is riveting, and the authors capture the sometimes curious way that science progresses through an alternation of chance discoveries and systematic, goal-directed experiments. Students wondering whether they are cut out to become scientists ought to be encouraged by the diverse cast of characters involved in solving the mystery of bioluminescence...These are exciting times for biology, and this accessible and lively introduction conveys the sheer pleasure of discovery, as well as the enormous technological potential of fluorescent proteins." - Thomas G. Oertner, Nature"

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Amazon.com:  8 Rezensionen
7 von 7 Kunden fanden die folgende Rezension hilfreich
It's not just the story of a protein 20. Februar 2006
Von BP - Veröffentlicht auf Amazon.com
Format:Gebundene Ausgabe
This book consists of fascinating vignettes of an unlikely cast of characters: glow-obsessed scientists, lovers of microscopic worms, madcap Russians, and driven scholars. The book drops into each of their lives with keen reporting skills, and it culminates not only by leaving the reader with a detailed biography of the green protein, but also with a fascination for its awesome potential as science research continues to drive forward. The last chapter raises the provokative topic of mind control...

The authors draw the reader with them on a truly remarkable journey.
6 von 6 Kunden fanden die folgende Rezension hilfreich
Excellent reading 18. Februar 2006
Von B. Damitz - Veröffentlicht auf Amazon.com
Format:Gebundene Ausgabe
Best book I've read in a long time. Gruber and Pieribone do an excellent job of telling the fascinating story of the emergence of Green Fluorescent Protein, in down-to-earth language that doesn't require an advanced degree in science to understand. By tying together a series of seemingly isolated scientific discoveries throughout the world, the authors lay out the surprisingly interesting story of the many breakthroughs that led to the emerging use and dominance of the substance that has changed the world of science as we know it. I'd highly recommend this one, once you start it is hard to put down....very mind-stimulating!
5 von 5 Kunden fanden die folgende Rezension hilfreich
Making real science available to everyone 24. April 2006
Von S.T. - Veröffentlicht auf Amazon.com
Format:Gebundene Ausgabe|Von Amazon bestätigter Kauf
Pieribone and Gruber report the science of green fluorescent proteins (GFP) in a way not usually encountered for science writing...that is leaving you wanting to know what happens next. From the first historical inquiries about glowing organisms to the marvelous, present day biotechnological uses of GFP, the authors narrate the life histories and trench work of the scientists primarily responsible for the discovery and scientific progression of fluorescent proteins in a very reader-inviting manner: with a lot of human interest, just enough science to allow you to know what they're talking about, and tons of oustanding pictures. Upon finishing the book, a reader may feel both entertained and an expert in fluorescent protein science at the same time!

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