If you enjoyed the previous books don't hesitate in buying it, this is better.
I just read this book and I may say this is the best of the four books not only because of the quality (it is full colored and the kind of paper is better) but because of better jokes: Mike looking for a real job, Cecilia and her T.A. section, the eternal life in the lab (there is this remarkable joke about The Lab Hierarchy which, in my opinion, is the closest to reality of the book) and Tajel with a surprising romance.
This book also includes a game to play Bingo in an Academic Seminar, a very original idea for enjoying with your research group in some workshop you don't like.